Glutathione
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Lyophilized Glutathione Powder
Key Features
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≥ 98 % Purity (HPLC‑Verified): Ensures minimal impurities for reproducible antioxidant and enzymatic studies PubMedPMC.
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Lyophilized Format: Freeze‑drying preserves chemical integrity and guarantees a shelf life of ≥ 2 years when stored desiccated at −20 °C.
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Master Antioxidant: Scavenges ROS, lipid hydroperoxides, and heavy metals, protecting cellular components from oxidative damage PubMedPMC.
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Enzyme Cofactor: Required by glutathione peroxidases (GPx‑1/GPx‑4) to detoxify peroxides and by glutathione S‑transferases for xenobiotic conjugation PMCPMC.
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Dual Redox Function: Exists as reduced (GSH) and recycled oxidized (GSSG) forms, maintaining intracellular redox homeostasis PMCPubMed.
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Low Endotoxin: Validated for sensitive in vitro assays, minimizing confounding immune activation in cell culture.
Specifications
Attribute | Specification |
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Form | White to off‑white lyophilized powder |
Purity | ≥ 98 % (HPLC) |
Solubility | ≥ 50 mg/mL in water at 25 °C |
Molecular Weight | 307.32 Da |
CAS Number | 70‑18‑8 |
Storage | −20 °C, dry, protected from light (stable ≥ 2 yrs) |
Applications
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Cell Culture Supplement: Prevents oxidative‑stress artifacts in neuronal, immune, and stem cell models by replenishing intracellular GSH pools.
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Redox & Aging Research: Probes sirtuin and PARP pathways, models senescence, and evaluates antioxidant interventions in vitro and in vivo PMCPMC.
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Enzymatic & ELISA Standards: Serves as a quantitative substrate or cofactor in kinetic assays for GPx, GST, and glyoxalase enzymes PMCMP.
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Detoxification Studies: Supports phase II conjugation assays for drug‑metabolism and xenobiotic clearance research PMC.
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Synthetic Biology & Biochemical Engineering: Integrates into microfluidic reactors and metabolic‑flux analyses requiring tight redox control PMC.

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