BPC-157

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Lyophilized BPC-157 Powder

Overview

Lyophilized BPC‑157 is a 15‑amino‑acid peptide fragment (GEPPPGKPADDAGLV) derived from human gastric juice that promotes rapid tissue repair and cytoprotection across multiple organ systems PubMedPMC. It enhances tendon and ligament healing by up‑regulating growth hormone receptor expression and fibroblast outgrowth in tendon models PMCPubMed. BPC‑157 also protects gastrointestinal mucosa, restoring integrity in gastric and colonic ulcer models without toxicity PMCFrontiers.

Key Features

• Accelerated Wound & Tendon Healing
  BPC‑157 accelerates re‑epithelialization in full‑thickness skin wounds and enhances Achilles tendon repair via fibroblast migration and collagen alignment FrontiersPubMed.

• Pro‑Angiogenic Activity
  Promotes angiogenesis by activating VEGFR2–Akt–eNOS signaling, increasing endothelial tube formation, and improving blood‑flow recovery in ischemic models PubMedNature.

• Gastrointestinal Cytoprotection
  Restores gastric and intestinal mucosal integrity, closes fistulas, and counteracts steroid‑induced aggravation in gut‑injury assays FrontiersPMC.

• Anti‑Inflammatory Modulation
  Suppresses pro‑inflammatory cytokines (TNF‑α, IL‑6) and inhibits NF‑κB activation, reducing edema and oxidative stress in multiple tissue models PMCPMC.

• Neuroprotective Effects
  Counteracts ischemia/reperfusion brain injury and supports neuronal survival and rapid reperfusion following stroke in rodent studies PMCWiley Online Library.

Applications

• Tendon & Ligament Repair Models
  Evaluate fibroblast outgrowth, collagen deposition, and biomechanical strength in tendon explants and injury paradigms PubMedPhysiology Journals.

• Wound Healing & Skin Regeneration
  Use in dermal excision and burn models to quantify closure rate, scar quality, and angiogenesis FrontiersGut N Liver.

• Gastrointestinal Research
  Probe mucosal healing, ulcer resolution, and anastomosis integrity in gastric and colonic injury assays PMCMDPI.

• Inflammation & Pain Modulation
  Study cytokine expression, nociceptive thresholds, and inflammatory marker changes in pain and colitis models PMCScienceDirect.

• Vascular & Ischemia Studies
  Assess blood‑flow restoration, endothelial migration, and vessel density in hind‑limb ischemia and stroke reperfusion models PubMedPMC.

Specifications