Melanotan II

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Lyophilized Melanotan II Powder

Key Features

• Potent Melanocortin Agonist: Melanotan II binds MC1R–MC5R subtypes to stimulate eumelanin synthesis and provide controlled skin‑pigmentation effects in cellular and animal models Wikipedia.

• Rapid Tanning Response: Human trials report visible tanning of forehead, arms, and neck after low‑dose subcutaneous injections, without UV exposure PubMed.

• Sexual Arousal & Appetite Modulation: Demonstrates central MC4R‑mediated increases in sexual arousal and transient appetite suppression in healthy volunteers PubMed.

• Fast Pharmacokinetics: Subcutaneous dosing of Melanotan II yields absorption‑phase half‑lives of 0.07–0.79 h and elimination β‑phase half‑lives of 0.8–1.7 h, supporting pulse‑dosing protocols PubMed.

• Clean Safety Profile: Side effects are generally mild—facial flushing, nausea, yawning—and serious adverse events are rare when used under controlled research conditions PubMedPubMed.

Applications

• Pigmentation & Photoprotection Studies: Model melanin synthesis pathways, UV‑damage mitigation, and cosmetic formulation testing in skin explants and organotypic cultures PubMed.

• Neuroendocrine Research: Probe melanocortin system roles in energy balance, thermogenesis, and hypothalamic regulation of appetite PubMed.

• Sexual Function Assays: Investigate MC4R‑driven penile erection mechanisms and central arousal circuits in preclinical models PubMed.

• Toxicology & Safety Profiling: Assess off‑target sympathomimetic effects, renal and muscle toxicity risks, and dose‑limiting tolerability in animal studies PubMed.

• Pharmacokinetic Method Development: Validate HPLC and bioassay techniques for biphasic disposition profiling and clearance rate determination PubMed.

Specifications